Vitamin C-Induced Epigenetic Modifications in Donor NSCs Establish Midbrain Marker Expressions Critical for Cell-Based Therapy in Parkinson's Disease

Cultured neural stem/precursor cells (NSCs) are regarded as a potential systematic cell source to treat Parkinson's disease (PD). However, the therapeutic potential of these cultured NSCs is lost during culturing. Here, we show that treatment of vitamin C (VC) enhances generation of authentic m...

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Publicado en:Stem Cell Reports
Autores principales: Wulansari, Noviana, Kim, Eun-Hee, Sulistio, Yanuar Alan, Rhee, Yong-Hee, Song, Jae-Jin, Lee, Sang-Hun
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639382/
https://ncbi.nlm.nih.gov/pubmed/28943252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.017
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