Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway

Stroke, characterized by a disruption of blood supply to the brain, is a major cause of morbidity and mortality worldwide. Although humanin, a 24-amino acid polypeptide, has been identified to have multiple neuroprotective functions, the level of humanin in plasma has been demonstrated to decrease w...

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Gepubliceerd in:Exp Ther Med
Hoofdauteurs: Gao, Guang-Sheng, Li, Yun, Zhai, Heng, Bi, Jing-Wen, Zhang, Fu-Sen, Zhang, Xiao-Ying, Fan, Shao-Hua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639330/
https://ncbi.nlm.nih.gov/pubmed/29043002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4934
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