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Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway
Humanin (HN) is an anti-apoptotic peptide that suppresses neuronal cell death induced by Alzheimer's disease, prion protein fragments, and serum deprivation. Recently, we demonstrated that Gly(14)-HN (HNG), a variant of HN in which the 14th amino acid serine is replaced with glycine, can decrea...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575816/ https://ncbi.nlm.nih.gov/pubmed/18590709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.06.018 |
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