Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway

Humanin (HN) is an anti-apoptotic peptide that suppresses neuronal cell death induced by Alzheimer's disease, prion protein fragments, and serum deprivation. Recently, we demonstrated that Gly(14)-HN (HNG), a variant of HN in which the 14th amino acid serine is replaced with glycine, can decrea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xu, Xingshun, Chua, Chu Chang, Gao, Jinping, Chua, Kao-Wei, Wang, Hong, Hamdy, Ronald C., Chua, Balvin H.L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575816/
https://ncbi.nlm.nih.gov/pubmed/18590709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.06.018
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