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Sitagliptin ameliorates high glucose-induced cell proliferation and expression of the extracellular matrix in glomerular mesangial cells

Diabetic nephropathy (DN) is one of the most important causes that leads to end-stage renal disease and the efficacy of strategies currently available for the prevention of DN remains unsatisfactory. Sitagliptin (SIT), which is a dipeptidyl peptidase-4 inhibitor, exhibited a modest beneficial effect...

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Опубликовано в: :Exp Ther Med
Главные авторы: Zhang, Guan-Ying, Wang, Dong-Dong, Cao, Zheng, Wei, Tong, Liu, Chen-Xu, Wei, Qun-Li
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639317/
https://ncbi.nlm.nih.gov/pubmed/29042993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5002
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