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Genetic and Epigenetic Profiling Reveals EZH2-mediated Down Regulation of OCT-4 Involves NR2F2 during Cardiac Differentiation of Human Embryonic Stem Cells

Human embryonic (hES) stem cells are widely used as an in vitro model to understand global genetic and epigenetic changes that occur during early embryonic development. In-house derived hES cells (KIND1) were subjected to directed differentiation into cardiovascular progenitors (D12) and beating car...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pursani, Varsha, Pethe, Prasad, Bashir, Mohsin, Sampath, Prabha, Tanavde, Vivek, Bhartiya, Deepa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638931/
https://ncbi.nlm.nih.gov/pubmed/29026152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13442-9
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