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MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis
MCPH1 gene, mutated in primary microcephaly, regulates cell progression into mitosis. While this role has been extensively investigated in the context of DNA damage, its function during unperturbed cell cycles has been given less attention. Here we have analyzed the dynamics of chromosome condensati...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638862/ https://ncbi.nlm.nih.gov/pubmed/29026105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12793-7 |
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