Division-induced DNA double strand breaks in the chromosome terminus region of Escherichia coli lacking RecBCD DNA repair enzyme

Marker frequency analysis of the Escherichia coli recB mutant chromosome has revealed a deficit of DNA in a specific zone of the terminus, centred on the dif/TerC region. Using fluorescence microscopy of a marked chromosomal site, we show that the dif region is lost after replication completion, at...

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Gepubliceerd in:PLoS Genet
Hoofdauteurs: Sinha, Anurag Kumar, Durand, Adeline, Desfontaines, Jean-Michel, Iurchenko, Ielyzaveta, Auger, Hélène, Leach, David R. F., Barre, François-Xavier, Michel, Bénédicte
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638614/
https://ncbi.nlm.nih.gov/pubmed/28968392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006895
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