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Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans

Tubulins, the building block of microtubules (MTs), play a critical role in both supporting and regulating neurite growth. Eukaryotic genomes contain multiple tubulin isotypes, and their missense mutations cause a range of neurodevelopmental defects. Using the Caenorhabditis elegans touch receptor n...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Zheng, Chaogu, Diaz-Cuadros, Margarete, Nguyen, Ken C. Q., Hall, David H., Chalfie, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638583/
https://ncbi.nlm.nih.gov/pubmed/28835377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0424
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