TCR-independent functions of Th17 cells mediated by the synergistic actions of cytokines of the IL-12 and IL-1 families

The development of Th17 cells is accompanied by the acquisition of responsiveness to both IL-12 and IL-23, cytokines with established roles in the development and/or function of Th1 and Th17 cells, respectively. IL-12 signaling promotes antigen-dependent Th1 differentiation but, in combination with...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Yun Kyung, Landuyt, Ashley E., Lobionda, Stefani, Sittipo, Panida, Zhao, Qing, Maynard, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638524/
https://ncbi.nlm.nih.gov/pubmed/29023599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186351
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