Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways

BACKGROUND: Psoriasis vulgaris is an inflammatory skin disease mediated by Th1 and Th17 cytokines, yet the relative contribution of interferon (IFN)-γ, interleukin (IL)-17 and IL-22 on disease pathogenesis is still unknown. OBJECTIVES: In this study, we sought to identify the cytokines produced by s...

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Hauptverfasser: Nograles, K.E., Zaba, L.C., Guttman, E., Fuentes-Duculan, J., Suarez-Farinas, M., Cardinale, I., Khatcherian, A., Gonzalez, J., Pierson, K.C., White, T.R., Pensabene, C., Coats, I., Novitskaya, I., Lowes, M.A., Krueger, J.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724264/
https://ncbi.nlm.nih.gov/pubmed/18684158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2133.2008.08769.x
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