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Role of the N-terminus for the stability of an amyloid-β fibril with three-fold symmetry
A key player in Alzheimer’s disease is the peptide amyloid-beta (Aβ), whose aggregation into small soluble oligomers, protofilaments, and fibrils finally leads to plaque deposits in human brains. The aggregation behavior of Aβ is strongly modulated by the nature and composition of the peptide’s envi...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638522/ https://ncbi.nlm.nih.gov/pubmed/29023579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186347 |
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