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Implementing Algorithm-Guided Warfarin Dosing in an Ethnically Diverse Patient Population Using Electronic Health Records and Preemptive CYP2C9 and VKORC1 Genetic Testing

Implementation of pharmacogenetic-guided warfarin dosing has been hindered by inconsistent results from reported clinical trials and a lack of available algorithms that include alleles prevalent in non-white populations. However, current evidence indicates that algorithm-guided dosing is more accura...

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Podrobná bibliografie
Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Obeng, A Owusu, Kaszemacher, T, Abul-Husn, NS, Gottesman, O, Vega, A, Waite, E, Myers, K, Cho, J, Bottinger, EP, Ellis, SB, Scott, SA
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638436/
https://ncbi.nlm.nih.gov/pubmed/27393744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.425
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