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Lmo2 modulates Sphk1 and promotes endothelial cell migration

OBJECTIVE: Lim-domain only (Lmo)2 transcription factor is involved in hematopoiesis and vascular remodeling. Sphingosine kinase (Sphk)1 phosphorylates sphingosine to sphingosine-1-phosphate (S1P). We hypothesized that Lmo2 regulates Sphk1 to promote endothelial cell (EC) migration and vascular devel...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Matrone, Gianfranco, Meng, Shu, Gu, Qilin, Lv, Jie, Fang, Longhou, Chen, Kaifu, Cooke, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637529/
https://ncbi.nlm.nih.gov/pubmed/28775072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309609
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