Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling

Sodium deficiency increases angiotensin II (ATII) and aldosterone, synergistically stimulating its retention and consumption. Recently, ATII-responsive neurons in the subfornical organ (SFO) and aldosterone-sensitive neurons in the nucleus of the solitary tract (NTS(HSD2) neurons) were shown to driv...

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Pubblicato in:Neuron
Autori principali: Resch, Jon M., Fenselau, Henning, Madara, Joseph C., Wu, Chen, Campbell, John N., Lyubetskaya, Anna, Dawes, Brian A., Tsai, Linus T., Li, Monica M., Livneh, Yoav, Ke, Qingen, Kang, Peter M., Fejes-Tóth, Géza, Náray-Fejes-Tóth, Anikó, Geerling, Joel C., Lowell, Bradford B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637454/
https://ncbi.nlm.nih.gov/pubmed/28957668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.09.014
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