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Identify Huntington’s disease associated genes based on restricted Boltzmann machine with RNA-seq data

BACKGROUND: Predicting disease-associated genes is helpful for understanding the molecular mechanisms during the disease progression. Since the pathological mechanisms of neurodegenerative diseases are very complex, traditional statistic-based methods are not suitable for identifying key genes relat...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Jiang, Xue, Zhang, Han, Duan, Feng, Quan, Xiongwen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637347/
https://ncbi.nlm.nih.gov/pubmed/29020921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1859-6
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