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Incorporation of functional elements enhances the antitumor capacity of CAR T cells

As chimeric antigen receptor (CAR) T cells have displayed an unprecedented efficacy in the treatment of CD19-positive malignances, it is believed that this cell therapy will be a milestone in the history of mankind’s conquering of cancer. However, there are some issues that restrict CAR T cells from...

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Detalles Bibliográficos
Publicado en:Exp Hematol Oncol
Main Authors: Qin, Le, Zhao, Ruocong, Li, Peng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637271/
https://ncbi.nlm.nih.gov/pubmed/29046826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-017-0088-z
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