CAR-T design: Elements and their synergistic function

Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically approved CAR-T–cell therapies have significant clinical efficacy in treating CD19-positive B cell cancers. With widespread interest to deploy this immunot...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Jayaraman, Jayapriya, Mellody, Michael P., Hou, Andrew J., Desai, Ruchi P., Fung, Audrey W., Pham, An Huynh Thuy, Chen, Yvonne Y., Zhao, Weian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393540/
https://ncbi.nlm.nih.gov/pubmed/32739874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102931
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