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Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome

Activity-dependent synaptic plasticity plays a critical role in the refinement of circuitry during postnatal development and may be disrupted in conditions that cause intellectual disability, such as Down syndrome (DS). To test this hypothesis, visual cortical plasticity was assessed in Ts65Dn mice...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: William, Christopher M., Saqran, Lubna, Stern, Matthew A., Chiang, Charles L., Herrick, Scott P., Rangwala, Aziz, Albers, Mark W., Frosch, Matthew P., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637117/
https://ncbi.nlm.nih.gov/pubmed/28899917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1045-17.2017
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