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Prying into the Prion Hypothesis for Parkinson's Disease
In Parkinson's disease, intracellular α-synuclein inclusions form in neurons. We suggest that prion-like behavior of α-synuclein is a key component in Parkinson's disease pathogenesis. Although multiple molecular changes are involved in the triggering of the disease process, we propose tha...
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| Published in: | J Neurosci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5637113/ https://ncbi.nlm.nih.gov/pubmed/29021298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1788-16.2017 |
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