An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

The innate inflammatory response must be tightly regulated to ensure effective immune protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has been associated with immune-related malignancies. Here, we describe a miRNA-based regulatory network that enables precise...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Mann, Mati, Mehta, Arnav, Zhao, Jimmy L., Lee, Kevin, Marinov, Georgi K., Garcia-Flores, Yvette, Lu, Li-Fan, Rudensky, Alexander Y., Baltimore, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636846/
https://ncbi.nlm.nih.gov/pubmed/29021573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00972-z
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