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The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation

The renal sodium chloride cotransporter, NCC, in the distal convoluted tubule is important for maintaining body Na(+) and K(+) homeostasis. Endogenous NCC is highly ubiquitylated, but the role of individual ubiquitylation sites is not established. Here, we assessed the role of 10 ubiquitylation site...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Rosenbaek, Lena L., Rizzo, Federica, Wu, Qi, Rojas-Vega, Lorena, Gamba, Gerardo, MacAulay, Nanna, Staub, Olivier, Fenton, Robert A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636807/
https://ncbi.nlm.nih.gov/pubmed/29021560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12819-0
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