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The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation
The renal sodium chloride cotransporter, NCC, in the distal convoluted tubule is important for maintaining body Na(+) and K(+) homeostasis. Endogenous NCC is highly ubiquitylated, but the role of individual ubiquitylation sites is not established. Here, we assessed the role of 10 ubiquitylation site...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636807/ https://ncbi.nlm.nih.gov/pubmed/29021560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12819-0 |
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