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The role of α(1)- and α(2)-adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats
BACKGROUND: Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D(2)-like receptors, serotonin 5-HT(1/2) receptors and α(1)/α(2)-adrenoceptors. Since activation of vascular α(1)/α(2)-adrenoceptors results in systemic vasopressor responses, the purpose of this s...
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Publicado no: | J Headache Pain |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Milan
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636772/ https://ncbi.nlm.nih.gov/pubmed/29022279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-017-0812-4 |
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