A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K(+) channels in carbon monoxide–induced proarrhythmic early afterdepolarizations

Exposure to CO causes early afterdepolarization arrhythmias. Previous studies in rats have indicated that arrhythmias arose as a result of augmentation of the late Na(+) current. The purpose of the present study was to examine the basis for CO-induced arrhythmias in guinea pig myocytes in which acti...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Al-Owais, Moza M., Hettiarachchi, Nishani T., Kirton, Hannah M., Hardy, Matthew E., Boyle, John P., Scragg, Jason L., Steele, Derek S., Peers, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636698/
https://ncbi.nlm.nih.gov/pubmed/28743763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700259R
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky