Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner

Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth. Considering the importance of a...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Vandereyken, Maud, Jacques, Sophie, Van Overmeire, Eva, Amand, Mathieu, Rocks, Natacha, Delierneux, Céline, Singh, Pratibha, Singh, Maneesh, Ghuysen, Camille, Wathieu, Caroline, Zurashvili, Tinatin, Sounni, Nor Eddine, Moutschen, Michel, Gilles, Christine, Oury, Cécile, Cataldo, Didier, Van Ginderachter, Jo A., Rahmouni, Souad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636116/
https://ncbi.nlm.nih.gov/pubmed/29020102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185786
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