Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner

Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth. Considering the importance of a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vandereyken, Maud, Jacques, Sophie, Van Overmeire, Eva, Amand, Mathieu, Rocks, Natacha, Delierneux, Céline, Singh, Pratibha, Singh, Maneesh, Ghuysen, Camille, Wathieu, Caroline, Zurashvili, Tinatin, Sounni, Nor Eddine, Moutschen, Michel, Gilles, Christine, Oury, Cécile, Cataldo, Didier, Van Ginderachter, Jo A., Rahmouni, Souad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636116/
https://ncbi.nlm.nih.gov/pubmed/29020102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185786
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