Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner

Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth. Considering the importance of a...

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Udgivet i:PLoS One
Main Authors: Vandereyken, Maud, Jacques, Sophie, Van Overmeire, Eva, Amand, Mathieu, Rocks, Natacha, Delierneux, Céline, Singh, Pratibha, Singh, Maneesh, Ghuysen, Camille, Wathieu, Caroline, Zurashvili, Tinatin, Sounni, Nor Eddine, Moutschen, Michel, Gilles, Christine, Oury, Cécile, Cataldo, Didier, Van Ginderachter, Jo A., Rahmouni, Souad
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636116/
https://ncbi.nlm.nih.gov/pubmed/29020102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185786
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