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Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1
Sirtuins (Sirt1–Sirt7) are NAD(+)-dependent protein deacetylases/ADP ribosyltransferases, which play decisive roles in chromatin silencing, cell cycle regulation, cellular differentiation, and metabolism. Different sirtuins control similar cellular processes, suggesting a coordinated mode of action...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635888/ https://ncbi.nlm.nih.gov/pubmed/28923965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706945114 |
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