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The BvgAS Regulon of Bordetella pertussis

Nearly all virulence factors in Bordetella pertussis are activated by a master two-component system, BvgAS, composed of the sensor kinase BvgS and the response regulator BvgA. When BvgS is active, BvgA is phosphorylated (BvgA~P), and virulence-activated genes (vags) are expressed [Bvg(+) mode]. When...

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Publicat a:mBio
Autors principals: Moon, Kyung, Bonocora, Richard P., Kim, David D., Chen, Qing, Wade, Joseph T., Stibitz, Scott, Hinton, Deborah M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635692/
https://ncbi.nlm.nih.gov/pubmed/29018122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01526-17
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