N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione

N-acetyl-l-cysteine (NAC) exhibits protective properties in brain injury models and has undergone a number of clinical trials. Most studies of NAC have focused on neurons. However, neuroprotection may be complemented by the protection of astrocytes because healthier astrocytes can better support the...

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Publicado en:Mol Pharmacol
Autores principales: Gleixner, Amanda M., Hutchison, Daniel F., Sannino, Sara, Bhatia, Tarun N., Leak, Lillian C., Flaherty, Patrick T., Wipf, Peter, Brodsky, Jeffrey L., Leak, Rehana K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635514/
https://ncbi.nlm.nih.gov/pubmed/28830914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109926
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