Heat shock protein responses to aging and proteotoxicity in the olfactory bulb

The olfactory bulb is one of the most vulnerable brain regions in age-related proteinopathies. Proteinopathic stress is mitigated by the heat shock protein (Hsp) family of chaperones. Here we describe age-related decreases in Hsc70 in the olfactory bulb of the female rat and higher levels of Hsp70 a...

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Bibliografske podrobnosti
izdano v:J Neurochem
Main Authors: Crum, Tyler S., Gleixner, Amanda M., Posimo, Jessica M., Mason, Daniel M., Broeren, Matthew T., Heinemann, Scott D., Wipf, Peter, Brodsky, Jeffrey L., Leak, Rehana K.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464935/
https://ncbi.nlm.nih.gov/pubmed/25640060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13041
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