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DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway
Fanconi Anemia (FA) is a rare, inherited genomic instability disorder, caused by mutations in genes involved in the repair of interstrand DNA crosslinks (ICLs). The FA signaling network contains a unique nuclear protein complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer...
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| Veröffentlicht in: | Cell Commun Signal |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635482/ https://ncbi.nlm.nih.gov/pubmed/29017571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0195-9 |
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