Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method

Changes in mitochondrial DNA (mtDNA) content is a useful clinical biomarker for various diseases, however results are controversial as several analytical factors can affect measurement of mtDNA. MtDNA is often quantified by taking ratio between a target mitochondrial gene and a reference nuclear gen...

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Publicat a:Biomol Detect Quantif
Autors principals: Memon, Ashfaque A., Zöller, Bengt, Hedelius, Anna, Wang, Xiao, Stenman, Emelie, Sundquist, Jan, Sundquist, Kristina
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
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Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634817/
https://ncbi.nlm.nih.gov/pubmed/29021970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bdq.2017.08.001
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