Neurotoxic Effects of Platinum Compounds: Studies in vivo on Intracellular Calcium Homeostasis in the Immature Central Nervous System

Platinum compounds cause significant clinical neurotoxicity. Several studies highlight neurological complications especially in paediatric oncology patients with Central Nervous System (CNS) and non-CNS malignancies. To understand the toxicity mechanisms of platinum drugs at cellular and molecular l...

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Publicat a:Toxics
Autors principals: Bernocchi, Graziella, Fanizzi, Francesco P., De Pascali, Sandra A., Piccolini, Valeria M., Gasperini, Caterina, Insolia, Violetta, Bottone, Maria Grazia
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634691/
https://ncbi.nlm.nih.gov/pubmed/29056659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxics3020224
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