A highly conserved amino acid in VP1 regulates maturation of enterovirus 71

Enterovirus 71 (EV71) is the major causative agent of hand, foot and mouth disease (HFMD) in children, causing severe clinical outcomes and even death. Here, we report an important role of the highly conserved alanine residue at position 107 in the capsid protein VP1 (VP1(A107)) in the efficient rep...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Zhang, Yong-Xin, Huang, Yu-Ming, Li, Quan-Jie, Li, Xiao-Yu, Zhou, Yong-Dong, Guo, Fei, Zhou, Jin-Ming, Cen, Shan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634653/
https://ncbi.nlm.nih.gov/pubmed/28938017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006625
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