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A highly conserved amino acid in VP1 regulates maturation of enterovirus 71

Enterovirus 71 (EV71) is the major causative agent of hand, foot and mouth disease (HFMD) in children, causing severe clinical outcomes and even death. Here, we report an important role of the highly conserved alanine residue at position 107 in the capsid protein VP1 (VP1(A107)) in the efficient rep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Zhang, Yong-Xin, Huang, Yu-Ming, Li, Quan-Jie, Li, Xiao-Yu, Zhou, Yong-Dong, Guo, Fei, Zhou, Jin-Ming, Cen, Shan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634653/
https://ncbi.nlm.nih.gov/pubmed/28938017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006625
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