A highly conserved amino acid in VP1 regulates maturation of enterovirus 71

Enterovirus 71 (EV71) is the major causative agent of hand, foot and mouth disease (HFMD) in children, causing severe clinical outcomes and even death. Here, we report an important role of the highly conserved alanine residue at position 107 in the capsid protein VP1 (VP1(A107)) in the efficient rep...

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Udgivet i:PLoS Pathog
Main Authors: Zhang, Yong-Xin, Huang, Yu-Ming, Li, Quan-Jie, Li, Xiao-Yu, Zhou, Yong-Dong, Guo, Fei, Zhou, Jin-Ming, Cen, Shan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634653/
https://ncbi.nlm.nih.gov/pubmed/28938017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006625
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