Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival

The E3 ubiquitin ligase RNF168 is a ring finger protein that has been previously identified to play an important regulatory role in the repair of double-strand DNA breaks. In the present study, an unbiased forward genetics functional screen in mouse granulocyte/macrophage progenitor cell line FDCP1...

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Veröffentlicht in:Biosci Rep
Hauptverfasser: Kizilors, Aytug, Pickard, Mark R., Schulte, Cathleen E., Yacqub-Usman, Kiren, McCarthy, Nicola J., Gan, Shu-Uin, Darling, David, Gäken, Joop, Williams, Gwyn T., Farzaneh, Farzin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634340/
https://ncbi.nlm.nih.gov/pubmed/28754805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170843
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