Combination therapy using molecular‐targeted drugs modulates tumor microenvironment and impairs tumor growth in renal cell carcinoma

Tumor growth and metastasis are determined not by cancer cells alone but also by a variety of stromal cells, various populations of which overexpress platelet‐derived growth factor receptors (PDGF‐Rs). In addition, activation of PI3K‐AKT‐mammalian target of rapamycin (mTOR) signaling is frequently o...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Kitano, Hiroyuki, Kitadai, Yasuhiko, Teishima, Jun, Yuge, Ryo, Shinmei, Shunsuke, Goto, Keisuke, Inoue, Shogo, Hayashi, Tetsutaro, Sentani, Kazuhiro, Yasui, Wataru, Matsubara, Akio
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633586/
https://ncbi.nlm.nih.gov/pubmed/28834289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1124
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi