ADAMTS5 Deficiency Protects Mice from Chronic Tobacco Smoking-Induced Intervertebral Disc Degeneration

STUDY DESIGN: ADAMTS5-deficient and WT mice were chronically exposed to tobacco smoke to investigate effects on intervertebral disc degeneration (IDD). OBJECTIVE: To demonstrate a role for ADAMTS5 in mediating tobacco smoking-induced IDD SUMMARY OF BACKGROUND DATA: We previously demonstrated that ch...

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Veröffentlicht in:Spine (Phila Pa 1976)
Hauptverfasser: Ngo, Kevin, Pohl, Pedro, Leme, Adriana S., Lee, Joon, Di, Y. Peter, Roughley, Peter, Robbins, Paul D., Niedernhofer, Laura J., Sowa, Gwendolyn, Kang, James D., Shapiro, Steven S., Vo, Nam V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633483/
https://ncbi.nlm.nih.gov/pubmed/28570296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0000000000002258
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