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Sexually Dimorphic Regulation of Osteoprogenitor Progesterone in Bone Stromal Cells

Augmenting peak bone mass is a promising strategy to prevent osteoporosis. A mouse model of global progesterone receptor (PR) ablation showed increased bone mass through a sex-dependent mechanism. Cre-Lox recombination was used to generate a mouse model of osteoprogenitor specific PR inactivation, w...

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Dades bibliogràfiques
Publicat a:J Mol Endocrinol
Autors principals: Kot, Alexander, Zhong, Zhendong Alex, Zhang, Hong Liang, Lay, Yu-An Evan, Lane, Nancy E, Yao, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633481/
https://ncbi.nlm.nih.gov/pubmed/28871061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-17-0076
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