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In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections

Monoclonal antibodies (mAbs) have wide clinical utility, but global access is limited by high costs and impracticalities associated with repeated passive administration. Here, we describe an optimized electroporation-based DNA gene transfer platform technology that can be utilized for production of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther Methods Clin Dev
मुख्य लेखकों: Andrews, Chasity D., Luo, Yang, Sun, Ming, Yu, Jian, Goff, Arthur J., Glass, Pamela J., Padte, Neal N., Huang, Yaoxing, Ho, David D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Gene & Cell Therapy 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633264/
https://ncbi.nlm.nih.gov/pubmed/29034261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.09.003
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