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In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections

Monoclonal antibodies (mAbs) have wide clinical utility, but global access is limited by high costs and impracticalities associated with repeated passive administration. Here, we describe an optimized electroporation-based DNA gene transfer platform technology that can be utilized for production of...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Andrews, Chasity D., Luo, Yang, Sun, Ming, Yu, Jian, Goff, Arthur J., Glass, Pamela J., Padte, Neal N., Huang, Yaoxing, Ho, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633264/
https://ncbi.nlm.nih.gov/pubmed/29034261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.09.003
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