TLR2/TLR4 activation induces Tregs and suppresses intestinal inflammation caused by Fusobacterium nucleatum in vivo

Toll-like receptors (TLRs) 2 and 4 play critical roles in intestinal inflammation caused by Fusobacterium nucleatum (F. nucleatum) infection, but the role of TLR2/TLR4 in regulation of proinflammatory cytokines remains unknown. In this study, through microarray analysis and qRT-PCR, we showed that T...

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Udgivet i:PLoS One
Main Authors: Jia, Yin-ping, Wang, Kun, Zhang, Zhu-jun, Tong, Ya-nan, Han, Dan, Hu, Chun-yu, Li, Qian, Xiang, Yang, Mao, Xu-hu, Tang, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633168/
https://ncbi.nlm.nih.gov/pubmed/29016688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186179
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