Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina

PURPOSE: We investigated the relationship between inflammation, neuronal loss, and expression of indoleamine 2, 3-dioxygenase (IDO) and quinolinic acid (QUIN) in the retina of subjects with type 1 diabetes (T1D) and type 2 diabetes (T2D) and in the retina of rats with T1D. METHODS: Retinas from T1D...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Hu, Ping, Hunt, Nicholas H., Arfuso, Frank, Shaw, Lynn C., Uddin, Mohammad Nasir, Zhu, Meidong, Devasahayam, Raj, Adamson, Samuel J., Benson, Vicky L., Chan-Ling, Tailoi, Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Retinal Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633007/
https://ncbi.nlm.nih.gov/pubmed/28980000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21654
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