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Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3
Interleukin-1 (IL-1) signaling induces the formation of Lys63-linked ubiquitin (K63-Ub) chains, which are thought to activate the ‘master’ protein kinase TGFβ-activated kinase 1 (TAK1) by interacting with its TAK1-binding 2 (TAB2) and TAB3 subunits. Here, we report that IL-1β can also activate the T...
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| Publicado no: | Biochem J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632801/ https://ncbi.nlm.nih.gov/pubmed/28507161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170288 |
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