Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expression and FGF signaling in the mid-hindbrain region...

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Detalles Bibliográficos
Publicado en:Front Neuroanat
Main Authors: Donovan, Alex P. A., Yu, Tian, Ellegood, Jacob, Riegman, Kimberley L. H., de Geus, Christa, van Ravenswaaij-Arts, Conny, Fernandes, Cathy, Lerch, Jason P., Basson, M. Albert
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632662/
https://ncbi.nlm.nih.gov/pubmed/29046629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00086
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