Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expression and FGF signaling in the mid-hindbrain region...

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Publicat a:Front Neuroanat
Autors principals: Donovan, Alex P. A., Yu, Tian, Ellegood, Jacob, Riegman, Kimberley L. H., de Geus, Christa, van Ravenswaaij-Arts, Conny, Fernandes, Cathy, Lerch, Jason P., Basson, M. Albert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632662/
https://ncbi.nlm.nih.gov/pubmed/29046629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00086
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