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Natural Killer Cells Unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy

Natural killer (NK) cells have long been known to mediate anti-tumor responses without prior sensitization or recognition of specific tumor antigens. However, the tumor microenvironment can suppress NK cell function resulting in tumor escape and disease progression. Despite recent advances in cytoki...

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Библиографические подробности
Опубликовано в: :Semin Immunol
Главные авторы: Davis, Zachary B., Vallera, Daniel A., Miller, Jeffrey S., Felices, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632228/
https://ncbi.nlm.nih.gov/pubmed/28882429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2017.07.011
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