Impact of Vancomycin Serum Trough Concentrations and Vancomycin AUC/MIC on Vancomycin Response, In-Hospital Outcomes and Acute Kidney Injury in Pediatric Staphylococcus aureus Pneumonia

BACKGROUND: Vancomycin AUC/MIC > 400 was initially shown to be beneficial in adults with staphylococcal pneumonia. Current practice guidelines recommend targeting serum vancomycin trough concentrations (VTC) of 15–20 µg/ml in adults with severe MRSA infection to approximate these AUC/MIC goals. S...

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Publié dans:Open Forum Infect Dis
Auteurs principaux: McNeil, Jonathon, Rosas, Louie, Hulten, Kristina, Mason, Edward O, Kaplan, Sheldon L
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631331/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx162.006
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