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Healthcare-associated Staphylococcus aureus bacteremia in children: Evidence for reverse vancomycin creep and impact of vancomycin trough levels on outcome

INTRODUCTION: Elevated vancomycin MICs in S. aureus have been associated with worse clinical outcomes in adults. For invasive MRSA infections in adults, the IDSA recommends targeting vancomycin serum trough concentrations between 15–20 μg/ml. We evaluated trends in vancomycin MICs from healthcare-as...

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Detalhes bibliográficos
Publicado no:Pediatr Infect Dis J
Main Authors: McNeil, J Chase, Kok, Eric Y, Forbes, Andrea, Lamberth, Linda, Hulten, Kristina G, Vallejo, Jesus G, Mason, Edward O, Kaplan, Sheldon L
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752422/
https://ncbi.nlm.nih.gov/pubmed/26646549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000000991
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